A Study of Thyroid Dysfunction in Metabolic Syndrome

Introduction: Metabolic syndrome is described as a cluster of abnormalities including abdominal obesity, insulin resistance, hypertension, hyperglycaemia, increased triglycerides, and decreased high-density lipoprotein cholesterol (HDL-C). Thyroid dysfunction is a risk factor for atherosclerotic cardiovascular disease mediated by the effects of thyroid hormones on lipid and glucose metabolism and blood pressure, hence on the components of metabolic syndrome. Objective: Present study was conducted to study thyroid dysfunctions in patients with metabolic syndrome attending SNMC and HSK hospital. Results: A total of 40 Patients with metabolic syndrome fulfilling IDF criteria were selected. Thyroid dysfunction was observed to occur in 17.5 % of metabolic syndrome patients. Prevalence of Subclinical hypothyroidism (12.5 %) and Overt Hypothyroidism (5.0 %) is observed in metabolic syndrome patients which is higher than that of general population. Conclusions: One sixth of metabolic syndrome patients had Subclinical Hypothyroidism. Prevalence of thyroid dysfunction is much more common in Females than males. Hence there is a need to exclude the presence of Thyroid dysfunction while managing metabolic syndrome patients.