A Prospective Study on Clinical Profile&Mortality Determinants of Acute Kidney Injury in Patients Attending Tertiary Care Center in Southern Rajasthan

Introduction: Although the term acute renal failure was replaced by Acute Kidney Injury (AKI) recently, there is a paucity of data on clinical profile of AKI in hospitalized patient from the developing world. The aims of this study was to study clinical profile, mortality determinants and the treatment protocol of patients of AKI. Methodology: It was a hospital based prospective observational study conducted in R. N. T. Medical College, from May 2017 to April 2018.250 patients admitted with AKI, defined according to the AKI Network criteria. The patients with AKI were followed-up until discharge/death. Their clinical and biochemical data were studied. Results: The common symptoms were fever (57.6 %), oliguria (38.4 %), GIT symptoms (38.0 %). The common aetiologies were AFI (45.6 %) followed by hypovolemia (22.4 %), sepsis (8.8 %). conservative treatment was done in 74.4 % of patients, 56 (22.4 %) were kept on hemodialysis and 7 (2.8 %) were kept on peritoneal dialysis. Overall mortality was 34.8 %. Conclusion: Timely diagnosis and management of this disease condition confer a favorable prognosis to the patient. The progression of AKI leads to increased hospital mortality rates and increased length of stays that might proved overuse of limited resources in a setting like India, more specifically in tribal part of Rajasthan. Hence more number of studies has to be done to efficiently pinpoint the predictors of AKI and preventing its occurrence in the near future.