Bcl-2 Expression in Skeletal Muscle in Diabetic Rats

Diabetic myopathy is a complication characterized by a decrease in muscle mobility and strength, which varies according to the severity of diabetes. ). In this study, histopathological changes and Bcl-2 expression in skeletal muscle in diabetic rats were shown. Rats were randomly assigned to two groups as control and diabetes group. Control group was allowed to feed at libitum for chow and water for 8 weeks. Single dose STZ (Streptozotocin 55mg/kg) was dissolved in sodium citrate buffer and intraperitoneally administered to diabetic rats. Glucose values of both groups were compared. Rats in diabetic groups has significantly higher glucose concentration (p