Comparison of the Intubating Conditions and Changes in the Haemodynamic Responses Following Larygoscopy and Intubation with or Without Pretreatment of Magnesium Sulphate

AIM: To compare the intubating conditions and haemodynamic conditions following laryngoscopy and intubation with or without pretreatment of magnesium sulphate in adult patients. METHODS: This study was conducted in the Department of Anaesthesiology, RIMS, Ranchi, Jharkhand, India during 2007-2009. It was a prospective, randomized, double- blinded study in which 50 adult patients of age group 18-60 years undergoing various elective routine surgery were undertaken randomly. Out of these, 25 patients were given magnesium sulphate infusion i. v i. e Group I (MgSO4 Group) and the remaining 25 were given saline infusion i. v i. e Group II (Control Group). An anaesthesiologist, blinded to the group assignment, performed direct laryngoscopy and endotracheal intubation and intubating conditions were assessed. Heart rate (HR) and Mean arterial blood pressure (MAP) were recorded before induction, after induction, just after intubation and 2 minutes after intubation. RESULTS: The two groups were comparable in their demographic profiles and airway features. There was improved intubating conditions in Group I patients when compared to Group II patients. The result was considered to be statistically significant (P