Ocular Manifestations in Rheumatoid Arthritis and their Co-Relation with Anti Cyclic Citrullinated Peptide Antibodies

Aims& Objective: To study ocular manifestations in RA& co- relate with Anti CCP Ab. Materials& Method: 114 patients attending Rheumatology& Ophthalmology OPD of a tertiary care hospital were screened. Examination and tests: Detailed slit lamp examination, BCVA by Snellen's chart, IOP taken by Goldman's tonomerty. Schirmer's& ocular staining score done. Dilated fundus examined by IDO. Chi square test used to co - relate their significance& P value calculated. Results: 42.10 % (48) of 114 cases had ocular manifestation. Dry eye being commonest 31.57 % (36) followed by cataract in 6 (5.26%) of cases.1 case each of Sjogren's syndrome& scleritis.1.75% (2) cases had peripheral keratitis, anterior uveitis& episcleritis each. Strong association seen between presence of Anti CCP Ab& ocular manifestation by significant P value Conclusion: Ocular manifestations are significant extra articular manifestation. Flaring up of ocular manifestation may signal impending deterioration or relapse of RA.