Co-Relation of Surgical Outcome and Impact of Er, Pr, Her-2/Neu&Ki-67 Expression in Carcinoma Breast

Breast cancer is the most common cancer diagnosed in women and the commonest cause of cancer related deaths all over the world. It is heterogenous disease with variable morphology and molecular features. Hence response to therpay also vary. The global cancer burden of cancer breast is also increasing instead of development of new treatment modalities. Methedology_ In this study stage 1, 2& 3 were included and stag 4 tumor, pt received chemotherapy or radiotherapy, recurrence were excluded. All pts followed normal protocol and subjected to MRM& followed by chemo& radiotherapy. Prognostic factors were estimated. Results_ 4 major groups were observed. ER+ve, PR+ve, HER-2/NEU +ve& Overexpression of Ki67. Worst prognosis with Tripple Negative. Poor prognosis in HER-2/NEU +ve. Recurrence rate is higher with Overexpression of Ki 67. Good prognosis in Tripple Positive.