QTc Interval, A Harbinger of Fatal Cardiac Events

Diabetes Mellitus is a common metabolic disorder. It is associated with pathophysiologic changes in multiple organ systems. Of primary concern is the cardiovascular disorders associated with diabetes mellitus. Even early in the course of diabetes, ECG alterations in the rhythm starting from simple sinus tachycardia and moving on to different ECG parameters like the prolongation of the classical QTc interval, or the QT dispersion, ST-segment and T-wave changes, alterations in heart rate variability, and presence of left ventricular hypertrophy, may be observed. The study was conducted on patients attending the outpatient department (OPD) and inpatients admitted in Yenepoya medical college Hospital. The study was conducted on 50 cases and 50 controls. Informed written consent was obtained from cases and controls for participation in the study and for conduct of investigations. A total of 106 subjects participated in the study, of which 53 were diabetic patients and remaining 53 non-diabetics. We did not observe a statistically significant pertaining to pulse rate among our two groups. Independent t-test was used to compare the QTc INTERVAL between the two groups. We observed a significant difference between the groups with a p value