Resistance Pattern and Epidemiological Characteristics of Cases of Malarial Fever in Jharkhanand

1. - Malaria is a protozoan disease transmitted by bite of infected Anopheles mosquitoes.2. Causative agents - Six species of the genus Plasmodium cause nearly all malarial infections in human. These are P. falciparum, P. vivax, P. ovale (two morphologically identical sympatric species), P. malariae and in Southeast Asia the monkey malaria parasite P. knowlesi (2) 3. Diagnosis- 1. Microscopy.2. Clinical diagnosis 3. Antigen detection test using rapid immunochromatographic techniques.4. Molelular test through PCR techniques.4. In this study we used the method microscopy for diagnosis of plasmodium falciparum malaria and parasite count, after that we started treatment artesunate, after complete course of treatment, again we used microscopy method for parasite count to know the affect of artesunate in parasite reduction. Results Male were 59.7 % and female were 40.3 % in total cases of malarial fever in Jharkhand. Under age 20 years were 15.3 %, between age 20-40 years were 43 %, between 40-60 years were 33 % and above 60 years were 08.3 % in total cases of malarial fever in Jharkhand. Malarial parasite count / microlit on day 1 before artesunate were Less than 1 lakhs 34.7 % 1 lakhs to 2 lakhs 34.7 % More than 2 lakhs 30.6 % MALARIAL PARASITE COUNT/ MICROLIT ON DAY 14 AND DAY 28 AFTER ARTESUNATE WAS ZERO, so artesunte is an effective drug for treatment of malarial fever in Jharkhand Most of malarial patients were from rural 59.7 % and urban patients were 40.2 % in total cases of malarial fever in Jharkhand Blood Urea abnormality were normal in 41.6 %, mild elevated in 40.8 %, moderate elevated in 4.2 % and severe elevated in 14.1 % in total cases of malarial fever in Jharkhand Serum creatinine were normal in 33.3 %, mild elevated in 36.1 %, moderate elevated in 27.8 % and severe elevated in 2.7 % in total cases of malarial fever in Jharkhand. Haemoglobin were normal in 20.8 %, mild anaemia in 23.6 %, moderate anaemia in 47.2 % and severe anaemia in 08.3 % in total cases of malarial fever in Jharkhand