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Effect of Vitamin C and Dialium guineense Fruit Pulp Activity on HO-1, Insulin Secretion and Ace in Experimental Diabetes

Journal: International Journal of Science and Research (IJSR) (Vol.7, No. 9)

Publication Date:

Authors : ; ; ; ;

Page : 355-361

Keywords : Hemeoxygenase; angiotensin converting enzyme; Dialium guineense; Diabetes; Vitamin C;

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The study was targeted at evaluating the modulatory effect of aqueous fruit pulp of Dialium guineense on hemeoxygenase, insulin, angiotensin converting enzyme (ACE) and possible hypoglycemia in streptozotocin-induced diabetic rats. Twenty four male Wistar rats were randomly divided into four groups control, diabetic control (Dm), diabetic + 300 mg/kg body weight Dialium guineese (Dm+ DG) and diabetic + 500 mg/kg Vitamin C (Dm +Vit. C). Animals were made diabetic by injecting a single dose of 55 mg/kg streptozotocin intraperitoneally. Dialium and Vitamin C were administered orally for three weeks. Result showed significant (p

Last modified: 2021-06-28 19:56:54