Clinical and Experimental Studies of the Effect of Honey on the Healing of the Oral MucosaJournal: International Journal of Science and Research (IJSR) (Vol.7, No. 10)
Publication Date: 2018-10-05
Authors : El bouhairi M.; Sidqui M.; Aboussaouira T.;
Page : 1005-1011
Keywords : Honey; antibacterial; wound healing; oral mucosa;
In dentistry, post-extraction infections are diverse and uncertain etiology. The management of these conditions is complicated, painful and often costly for the patient and the practitioner. Because honey is a natural product, abundant in our country and Moroccan people has confidence in his virtues, the question arose on the value of honey in the treatment and prevention of post-extraction infections. A protocol for evaluating the effect of honey on the healing of the oral mucosa has been developed and honed by two experimental studies by taking the thyme honey as a reference In vitro study -An evaluation of fibroblast culture proliferation and cell growth in honey. -An evaluation of bacterial growth in honey. Clinical study -Immediate honey installation in alveolar wounds, in patients with apparent good condition and good oral hygiene. Clinical inspection and tissue samples will be made after 21days. The results of our study have shown that the thyme honey has a healing and antibacterial activity of several bacterial strains. These results are consistent with data from the literature. As against the in vitro study showed a cytotoxicity of fibroblast cells in the presence of honey (2 % and 10 %), which is probably due to high osmolarity of honey.
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