Review: Biomimetic Approach for Remineralization of Human Enamel

Biomimetic mineralization is a methodology that imitates the natural process of mineralization. The biomimetic synthesis of enamel-like apatite structures under a physiological condition is an attractive, bioavailable alternative of repairing defective enamel. During the last several years different biomimetic systems for enamel remineralization were developed. They are based on amelogenin, other peptides, dendrimers, amino acids, calcium phosphate nanoparticles and others. Despite all the promising studies, described in this systematic review, the biomimetic strategies still face ongoing challenges in the fields of dentistry and material sciences.