Clinical Use of Triple Antibiotic Paste in Dentistry

As intra canal medicament have shown very encouraging results the use of triple antibiotic paste (is a mixture of ciprofloxin, metronidazole and minocycline) is widely used nowadays. Due to complex polymicrobial nature of infected root canal combination of antibacterial drug is required. Recent advances in lesion sterilization and repair using triple antibiotic paste has repress the root canal pathogen to allow healing of periapical lesion. This paper analysis the rationale of antibiotic mixture, antibacterial efficiency, current application, advantages over calcium hydroxide and disadvantages.