25 Hydroxy Vitamin D Insufficiency and Deficiency in Stages of Chronic Kidney Disease Patients in Nepal

Background: Vitamin D is a sunshine vitamin. Vitamin D insufficiency and deficiency in chronic kidney disease (CKD) patients and also in normal renal functions in tropical regions3, 4, 5. The aim of this study was to determine the relation between the 25 (OH) vitamin D insufficiency and deficiency with the Nepalese patients of chronic kidney disease. Materials and Methods: A cross sectional descriptive study was designed from April to September 2018. Total 216 Chronic Kidney Patients were involved in this study. After taking consent from the patients and hospitals, we were collected blood samples from the patients and were analysed the Variables like 25 OH Vitamin D, Calcium, Phosphorus, Urea, Creatinine and Albumin. Data were analysed by using SPSS for Windows for different variables. Result: 216 chronic kidney Disease (CKD) patients were enrolled, 42 % male and 58 % female with mean age was 48.21 15.45 and mean 25 (OH) Vitamin D was 20.54 12.12.25 (OH) Vitamin D deficiency (0.05). Vitamin D deficiency and Insufficiency were also insignificant differences in CKD stages. (Pgreater than0.05). Phosphorous is negative correlation to 25 (OH) Vitamin D (r value -0.025 and P greater than0.927), whereas corrected Calcium is significant (r value 0.156 and P 0.023). Conclusion: Result of our present study indicated that vitamin D levels below the recommended values observed in stages of CKD