Histopatological Profile in Patient with Chronic Gastritis Who Underwent EGD in Wangaya Hospital Using Sydney System

: Gastritis is an inflammation of the lining of the gastric mucosa and submucosal. The Sydney system classified gastritis with three combination histological division: etiology, topography, and morphology. The aim of this study to show the histopatologic profile in dyspepsia patient who went esophagogastroduodenoscopy in Wangaya Hospital with Sydney System. This descriptive study conducted on 200 patient with dyspepsia syndrome between January 2018 and June 2018 who doesnt respond with PPI therapy for 4 weeks. All patient underwent esophagogastroduodenoscopy and biopsies were taken on antrum, and corpus using Hematoxylin and Eosin, and Giemsa stain for grading of various parameters and for detection of HP. Our research show that H. Pylori can be one of the cause of dyspepsia in 27 patient (13.5 %), which antrum is the most 24 patients (88 %). The most common age group affected by H Pylori was 41- 50 years constituting 29, 6 % of cases. The majority (67.56 %) of the biopsies showed marked inflammation; 28.2 % had moderate inflammation and there is no atrophy in this study (0 %). In H Pylori infection correlated to marked inflammation, high activity of neutrophil and no atrophy process. The esophagogastroduodenoscopy needs to be done in patients with dyspepsia symptoms that untreatable with PPI therapy.