Association of Fatty Liver and Hypothyroidism

AIM The aim of this study was to evaluate the association of thyroid dysfunction on the development of fatty liver. OBJECTIVE The main objective of this study is to determine the relationship of abnormal liver function, fatty liver among subclinical and overt hypothyroid patients BACKGROUND Thyroid hormones are totally involved in the regulation of body weight, lipid metabolism, and insulin resistance. The liver plays a crucial role in the metabolism of cholesterol and triglycerides, thyroid hormones interact on hepatic lipid homeostasis. Therefore it is anticipated that thyroid hormones may have a role in the pathogenesis of non alcoholic fatty liver disease (NAFLD). Hypothyroidism confers an increased risk of non-alcoholic fatty liver disease (NAFLD). REASON Non-alcoholic fatty liver disease (NAFLD) represents one of the most common chronic disorders of the liver. Various literatures provide evidence that hypothyroidism is reported to contribute to the development of fatty liver. Thus this study is done to confirm those findings and for early diagnosis and prevent complications.