Histopathological Spectrum of Lesions in Nephrectomies? A Five Year Study

Introduction The indications of nephrectomy include different conditions such as irreversibly damaged kidney in chronic infections, obstruction, calculus disease or severe traumatic injury. Other indications include unilateral parenchymal damage due to nephrosclerosis, pyelonephritis, vesicouretricreflux and renal cell carcinoma. Objective The aim of this study is to categorize the different histopathological conditions observed in the nephrectomy specimens and their clinico- morphological correlation over a period of five years so as to study the indications and prevailance of different conditions in our centre and compare with studies conducted elsewhere. Material and methods-A total of 65 nephrectomy specimens over a period of five years were included in our study ( January 2011 to December 2015). The clinical details and all relevant data were considered. Result-Benign conditions which led to nephrectomy were seen in 27 cases and malignant in 38 cases. The male female ratio was 1.71 Conclusion- In our study the commonest indication of nephrectomy was renal cell carcinoma with a total of 30 cases followed by chronic pyelonephritis which was found in 17 cases. The relative decrease in benign cases was due to better non invasive and early management of benign conditions.