Histopathological and Colposcopic Correlation for Cervical Lesions at Tertiary Care Centre in Central Part of India

Objectives Aim of the present study is to detect the role of colposcopy and cytology in early detection cervical lesions (benign and malignant) with following objectives 1. Clinical study of benign and malignant cervical lesions.2. To differentiate between benign and malignant cervical lesions.3. To study the correlation of colposcopic appearance with histopathology Methods It was Hospital based, short term, prospective study. This study was carried out at Bhandari Hospital and Research Centre and Associated Hospitals, Indore, patients attending OPD of Obstetric and Gynaecology department and undergone for colposcopy and cytology of cervix from november 2012 to October 2014. Results In present study 225 patients were inciuded, out of them 45.33 % patients were in age group of 30-40 years. Majority of patient 44 % were illiterate.53.33 % patients had first sexual intercourse before 15 years of age. most common complaint was discharge per vaginum followed by pain in lower abdomen. Colposcopy and colpocopy directed biopsy done accordingly and correlation made. For CIN-1 correlation was 66.67 %, for CIN-2 it was 85.71 % and for CIN -3 andinvasive cancer it was 100 %. Conclusions Colposcopic directed biopsy is considered as Gold standard method for confirmation of cervical intra-epithelial lesions. High grade lesions can be diagnosed by colposcopy more specifically most common drawback associated with colposcopy is over interpretation of the low grade lesions and over treatment because majority of these lesions regress spontaneously over the course of time and during follow up or with treatment. Therefore, combined approach (Pap smear, Colposcopy, Biopsy under colposcopic guidance) is recommended for the evaluation of suspicious cervical lesions and manage accordingly. Fortunately Cervical Cancer has long Pre-invasive phase and with the help of screening methods, Cervical lesions can be diagnosed early and mortality can be reduced or prevented. With recent advances and improvement in screening methods and improved awareness regarding cervical cancer, burden of the disease has been decreased in past few decades.