The Frequency of Acute Ischemic Mitral Regurgitation Post-Acute ST-Elevation Myocardial Infarction

Background. Acute ischemic mitral regurgitation is a recognized complication of acute myocardial infarction (MI). Aims. To evaluate the frequency of acute ischemic mitral regurgitation post- acute ST- elevation myocardial infarction (STEMI) and impact of thrombolytic therapy and predictive risk factors of (MI). Methods. This was a cross-sectional study that included patients who were admitted to the (CCU) of Baghdad Teaching Hospital with acute (STEMI), during the period from January 2016 to January 2017. After taking informed consents, demographic data were recorded including risk factors of MI. For treatment with thrombolytic, onset of chest pain was divided into (within 6 h, 7-12 h, and beyond treatment). A (2 dimensional) transthoracic echocardiogram was performed on third day of admission searching for ischemic mitral regurgitation, which was divided into mild, and moderate to severe. Results. Total sample was 117 patients with mean age of (56.0 14.6) years. From total, 85 (72.6 %) patients were males and 32 (27.4 %) were females. Thirty-four patients developed ischemic mitral regurgitation with frequency of 28.9 %. Age, smoking, and family history of ischemic heart disease did not show significant association with the development of ischemic mitral regurgitation while gender was significantly associated. Anterior and inferior MI were the most common found. Timing of thrombolytic therapy was significantly associated with development of ischemic mitral regurgitation. Conclusions. This study found that ischemic mitral regurgitation is a common complication of acute (STEMI). Thrombolytic therapy during the first 6 hours significantly affects the development of ischemic mitral regurgitation