Churg Strauss Syndrome presenting as an Eosinophilic Pleural Effusion
Journal: International Journal of Science and Research (IJSR) (Vol.2, No. 2)Publication Date: 2013-02-05
Authors : Deepak Nayak M; Sushma V. Belurkar; P. S. Srilatha; Indira Shastry; Girish Solanke;
Page : 510-512
Keywords : Churg-Strauss syndrome; eosinophilia; pleural effusion;
Abstract
Churg-Strauss syndrome (CSS) is a rare form of systemic vasculitis affecting themedium to small sized vessels. The diagnosis of this disease is based mainly on clinical grounds; comprising of asthma, peripheral blood and tissue eosinophilia, rhinosinusitis and signs of vasculitis in major organs. A 48 year old female patient on treatment for bronchial asthma, presented with a bilateral pleural effusion. The analysis of the fluid revealed an eosinophilic exudate (67%). The additional investigations revealed a raised Immunoglobulin E (IgE) levels and p-ANCA positivity. The presentation of CSS as eosinophilia in body fluids is rare and may herald the onset of the vasculitic phase of the disease.
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