Microwave Assisted Synthesis of Nitrogen and Hydroxyl Containing Bioactive Compounds as Drug MotifJournal: International Journal of Science and Research (IJSR) (Vol.3, No. 9)
Publication Date: 2014-09-05
Authors : Shahana Ehsan; Sehrish Gahfoor; Bushra Khan;
Page : 195-199
Keywords : Pyrazole; Alkanol; Microwave; Chalcone; Grignard reagents;
Organic compounds not only make up life on earth but a wide variety of classes also have healing properties like anti-bacterial, -diabetic fungal, -HIV, -inflammatory, -tubercular etc. This therapeutic importance of carbon containing moieties especially those containing nitrogen and hydroxyl functionalities attract researchers to explore more productive and reproducible synthetic avenues like microwave-assisted approach rather to remain focused on conventional processes that are time consuming and low in purity. Moreover, due to high consumption of chemicals for prolonged time, it adversely affects environment. This key reason forces chemists to adopt microwave-assisted synthesis to achieve desired compounds. This eco-friendly technique uses microwave irradiations that speed up reactions in comparatively less time and offers high yield of products with purity. This research proposal aimed to fabricate some bio-active organic compounds (Pyrazole and alkanol derivatives) via microwave-assisted methods using interesting synthetic schemes.
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