Study of Thyroid Dysfunction in Premenopausal Women with Abnormal Uterine Bleeding

ObjectiveTo evaluate incidence of thyroid dysfunction in abnormal uterine bleeding and to assess the menstrual patterns in women with thyroid disorders. Material & Methods Present prospective study was conducted on 113 patients who presented with abnormal uterine bleeding at Kamineni Institute of Medical Sciences, Narketpally. Results & Discussion Among 113 women, 43 had hypothyroidism, 9 patient had hyperthyroidism rest 61 were euthyroid. Of 43 hypothyroid patients, 27 (62.3 %) had menorrhagia, 4 had oligomenorrhea and 9 patient with hyperthyroidism was found to have oligomenorrhea & Hypomenorrhoea. Woman with hypothyroidism, commonly presents with anvoulation and unopposed oestrogen activity causes endometrial hyperplasia which may outgrow the blood supply and may cause local areas of necrosis that breaks down and produces bleeding. Conclusion The menstrual irregularities are significantly more frequent inpatients with thyroid dysfunction and menorrhagia was the commonest menstrual abnormality. The study concludes that biochemical evaluation of thyroid function should be made mandatory in all cases of AUB.