Analgesic, Anti-inflammatory and Anti-Pyretic Effects of Azadirachta indica (Neem) Leaf Extract in Albino Rats

Neem (Azadirachta indica), popularly known as Wonder tree is an evergreen tropical tree, which has been reported to have beneficial effects on various disease pathology from the ancient time. Such health benefits are the sum of molecular actions of the natural ingredients present in it. Among all ingredients azadirachtin, nimbidin, flavonoids, triterpenoids are notable for their beneficial effects against disease pathology. Neem has been reported to have anti-allergenic, anti-dermatic, anti-feedent, anti-fungal, anti-inflammatory, anti-pyorrhoeic, anti-scabic mode of actions. Besides these, neem is also beneficial for cardiac, diuretic, insecticidal, larvicidal, nematicidal, spermicidal and other biological activities. Though, here in the present study, our focus was only in three parameters i. e. , whether neem leaf extracts (NLE) can contribute to anti-analgesic, anti-inflammatory and antipyretic action in albino rats, which is a novel one. Our experimental observations revealed that NLE have analgesic, anti-inflammatory and antipyretic effects in Albino rats.