Compositional Analysis and Antimycobacterium Tuberculosis Activity of Essential Oil of Hyptis Suaveolens Lamiceae Obtained from North-East Nigeria

Fresh leaves of Hyptis suaveolens were collected and pretreated for essential oil analysis with the sole aim of linking the ethnomedicinal uses of this plant by the people of Adamawa State Nigeria to its essential oil composition. The results obtained from the analysis shows that 68 compounds were present in varying concentration out of which 16 compounds have appreciable concentration making 75.135 % of the total abundance. The major compound being Caryophyllene (20.643 %) followed by Sabinene (16.711 %) and Terpinolene (8.490 %). The essential oil of this plant also exhibited anti mycobacterium tuberculosis activity when tested on strain 7H9/ADC with MIC of 3.13 %. This activity was compared with standard drug Rifampicin which also has MIC of 0.1 g/ml.