Fabry's Disease: A Case Report and Review of Literature

Case history A 27 yr old male patient, pursuing his post graduation was referred from dermatology, with a chief complaint of small red raised lesions on flanks, abdomen and scrotum since the age of 12yrs. H/o present illness Skin lesions 1st appeared - flanks 15 years back. Lesions gradually progressive - involved scrotum, thighs and medial aspects of upper arms over 6 years period. h/o lethargy and tiredness present No h/o alterations in sweating No h/o episodes of abdominal pain and diarrhoea No h/o intolerance to cold and heat No h/o any growth abnormalities or developmental delay. No h/o defective vision. Past history burning and pricking sensation on hands and feet especially after physical stress, since the age of 5 yrs. No history of hypertension, diabetes mellitus, Coronary artery disease, cerebro vascular accidents. Personal History nil Family history nil particular