Histopathological Changes in the Liver and Kidney of Freshwater Teleost, Channa striatus (Bloch) on Exposure to Lead nitrate

The present study was conducted to investigate the histopathological changes in the liver and kidney of freshwater teleost, Channa striatus after exposure to 28 mg/l (10 % of 96 hrs LC50) of lead nitrate for a period of 30 and 60 days under laboratory conditions. The resultant histopathological changes in the liver and kidney were recorded by light microscope. The most common changes in the liver of fishes were severe loosening and necrosis of hepatic tissue, cytoplasmic vacuolation, expansion in cell size, eccentric and enucleated hepatocytes. Kidney of fishes exposed to 28 mg/l of lead nitrate was characterized by loosening and damage in haemopoietic tissue, deshaped and damaged renal tubules, necrosis, shrinkage in glomerulus, necrosis and enlarged Bowmans space. The present investigation illustrates that these histopathological changes would serve useful purpose in evaluating the toxic effects of lead nitrate.