Correlation between Clinical and Laboratory Data's of Infectious Mononucleosis - Like Syndrome

Infectious Mononucleosis (IM) is caused by EBV and usually affects children and young adults. Infectious Mononucleosis like Syndrome represents a clinical and laboratory manifestation of two or more infectious diseases of different etiologies (viral and non viral). Even though Infectious Mononucleosis is well-defined in all its aspects (clinical, hematological and serological), there are many Mononucleosis like Syndromes which are introduced with the same clinical and laboratory features (fever, sore throat, lymphadenopathy, splenomegaly, lymphocytosis and atypical polymorphonucleares in blood stream) We studied 104 patients hospitalized in our clinic as Mononucleosis like Syndrome. Discharge diagnoses resulted as Infective Mononucleosis 36.5 %, undifferentiated adenopathy 23 %, Toxoplasmosis 15.3 %, HIV 7.4 %, CMV 1.9 %, Streptococcal pharyngitis 1.9 %, follicular angina 7.4 %, acute leucosis 1.9 %. Clinical signs were dominated mainly by fever in 100 % of cases, sore throat in 36.17 %, adenopathy in 34.04 %, hepatosplenomegaly in 24.04 %.