Biomimetic Approaches of Dentin Regeneration

Dentin is a unique dental tissue in structure and composition that forms the main part of the teeth. Minimally invasive approaches today widely use enamel remineralization - a strategic concept in preventive treatment without restoration. The dentin remineralization is more complex but very promising for a variety of clinical applications. These aplications are dentin and root caries, dentin hypersensitivity, acid-etched dentin that is incompletely infiltrated by adhesives and partially demineralized as a result of a carious process (i. e. affected dentin), especially in deep carious lesion. In order for remineralizing biomimetic materials to be implemented clinically and for practical recommendations to be offered, fundamental research studies on dentin remineralization and regeneration are still needed.