A Comparative Study of the Role of Various Antibiotic Drugs in Drug Induced Liver Injury by Hepatotoxicity

Medicines associated with side effects include antibiotics, anticoagulants, tranquillisers and non-steroidal anti-inflammatory agents in cases of suspected liver reactions. It is essential to obtain a detailed drug history that includes awareness of the drug's hepatotoxic potential and the timing of drug administration in relation to the emergence of symptoms, previous administration of the antibiotic in question and concomitant drug use. Drug-induced liver injury (DILI) is a leading health problem especially in a globally expanding commercialization of new drugs and the increasing exposure of patients to new compounds. This is expected to increase because of the number of drugs being consumed, prescription and non-prescription, as well as because of the current tendency towards pharmacologically active complementary and alternative medicines, dietary supplements, recreational substances and special diets.