Colorectal Cancer: A Study of 206 Malignant Cases

Background Carcinoma of colon and rectum is one of the most common malignancies in the world and its incidence is rising in the countries that are adopting western life styles (1). The cause and pathogenesis of colorectal carcinoma are related to both environmental and genetic factors (2). There is a close relation between meat consumption and incidence of large bowel cancer (3). Other foods particularly vegetable fibre may be protective, Buskitt DP 1971. Genetic factors play a role possibly governing a proneness to adenoma development (4). Cancer is age related, the increasing age increase incidence, in high risk areas approximately 8 % of patients under the age of 50 years (5). A proportion of carcinomas arise within pre existing adenomas (6). Objective is to study the occurrence and Clinical pathological correlation of malignant tumours of colorectum. The methodology is retrospective four and prospective four years study of large intestine malignancies from 2007-2015. Results 206 (21.28 %) cases of colorectal malignancies out of 968 GIT malignancies with a peak in the 41-60 age groups. The male to female distribution ratio was 21. Conclusion Adenocarcinoma was the most common type of presentation 86.89 % (179) of all large bowel malignancies.