Ameliorating Effect of Bee Pollen against Anti-Tuberculosis drugs (Rifampicin and Isoniazid) Induced Toxicity on Haematology of Sprague Dawley Rats

Experimental male SD rats weighing 18020 g were randomly assigned into eight groups comprising of drug treated and bee pollen administered rats in selected test concentrations. Haemoglobin (Hb), red blood cell count (RBC Count) and white blood cell count (WBC Count) were then evaluated using standard techniques after 30 days of treatment. Result indicated that bee pollen feeding helped to improve blood parameters in normal rats. Further, the drugs rifampicin and isoniazid alone as well as in combination significantly lowered blood indices indicating toxicity. However, co- administration of bee pollen (100 mg bee pollen /kg body weight) definitely helped to ameliorate the toxic effects by restoring tested values to near normal.