Ossifying Fibromyxoid Tumor of Maxilla: A Case Report and Review of Literature

Objective Ossifying fibromyxoid tumor is a rare soft tissue tumor of uncertain differentiation with varied presentation at different sites. They behave in a benign fashion, however a small percentage of tumors may locally recur or metastatize. This paper reports an unusual site of ossifying fibromyxoid tumor. In the maxillofascial region, this tumor is rarely reported. Case report A 45years female presented with a right cheek swelling since 3 months which was clinically diagnosed as carcinoma of hard palate. Radiological examination showed expansile lytic lesion of alveolar process of right maxilla bulging into maxillary sinus. FNAC features were suspicious of odontogenic tumor. Biopsy tissue from this site showed features of Epulis. Patient underwent hemimaxillectomy. On histological examination, tumor showed oval to spindle shaped cells in abundant fibromyxoid stroma with focal areas of interstitial calcification. Tumor was covered by a thin rim of fibrocollagenous capsule along with focal areas of lamellar bone. Immunohistochemistry stain for Vimentin was positive. Final diagnosis of ossifying fibromyxoid tumor was made. Conclusion Ossifying fibromyxoid tumors are diagnosed with a combination of clinical, radiological and pathological criteria. The rarity of the lesion may lead the pathologists to misdiagnose. These tumors should be completely excised for thorough management as some of them show local recurrence after excision.