Effect of Lucronil? Tablets in the Patients with Leucorrhea: An Open Clinical Trial

Leucorrhoea is a common gynaecological problem causing discomfort and disturbance in day to day activities of women. In view of unavailability of specific treatment to manage the condition, we evaluated efficacy and safety of Tab. Lucronil on the clinical signs and symptoms of Leucorrhea. After obtaining Ethics Committee permission and written informed consent, a total of 31 patients were recruited in the study. These patients were asked about the color, odor, consistency and degree of vaginal discharge before and after the treatment. Cervical smear was also collected to assess inflammatory changes. Tab. Lucronil was administered as two tablets (500 mg) twice a day after meals with water for a period of one month. We observed that Tab. Lucronil reduced the symptoms of Leucorrhoea in 8 patients within the duration of 15 days. The remaining 23 patients showed significant reduction (p less than 0.001) in the degree of cervical discharge and inflammation (pless than0.01). There were no adverse effects reported during the study period. Tab. Lucronil was well tolerated by all the patients as evident from the good compliance. Our study thus highlights the efficacy and safety of Tab. Lucronil in leucorrhoea.