Lipid Profile among Sudanese Cigarette Smokers in Khartoum State, Sudan

It has proven that high level of LDL-C and low levels of HDL-cholesterol predispose individuals to the risk of coronary heart disease. Cigarette smoke contains toxicants that can disrupt normal metabolic process and cause dyslipidemia. The present study was undertaken to evaluate lipids profile among healthy Sudanese smoker in Khartoum state and to compare it with healthy non-smoker in the fasting state. This was across-sectional studies conducted during the period from May to October 2011. Fifty male smoker and fifty male non-smoker were recruited for the study after obtaining written informed consent. Both groups were age and weight matched. The serum levels of total cholesterol, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglycerides were assayed for each group using standard biochemical methods. The serum levels of total cholesterol, LDL-C and triglycerides were significantly raised in smoker group when compared to non-smoker group (Pless than0.05). Wheres the serum level of HDL-C were significantly reduced in the smoker group (Pless than0.01). There was a significantly strong positive correlation between the serum levels of total cholesterol, triglyceride and number of cigarette smoked per day and a significant moderate positive correlation between the serum levels of LDL-C and the number of cigarettes smoked per day. These finding indicate that smoking produce adverse effects on lipid profile, therefor increasing the risk of coronary heart disease.