A Case Report on Limited Wegner's Granulomatosis

Wegener's granulomatosis is an uncommon multi-systemic disease, characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tracts and general focal necrotizing vasculitis. We described a case of 32 years old women with pansinusitis, cough without expectoration, rhinitis and joint pain. Laboratory investigations serum cytoplasmic anti-neutrophil antibody (C-ANCA) and c - reactive protein (CRP) were positive. Radiological investigation put forth a diagnosis of wegener's granulomatosis. The patient was put on a combined therapy of prednisolone (1mg/kg) and cyclophosphamide (2mg/kg) for 2 months, which yielded positive results and provided symptomatic relief to the patient. The patient did not have renal involvement.