Metastatic Leiomyosarcoma of Gall Bladder: Rare Case Report

Introduction: Primary sarcomas of the gallbladder (GB) as a rare disease, the incidence of which is more in women than men. Case Report: A 52 -year-old female patient presented to the outpatient clinic with complaints of intermittent pain in the right upper quadrant of the abdomen, nausea and some weight loss for 2-3 months. Ultrasound revealed Gall bladder mass with liver invasion. CT and PET-CT scan revealed Periportal and omental deposits . Final diagnosis was reached by FNAC and IHC as Metastatic Leiomyosarcoma of Gall Bladder. She was advised palliative chemotherapy as the tumor was unresectable and in advanced stage. She refused for chemotherapy and eventually died 3 months after diagnosis. Discussion: LMS of Gall Bladder is a rare entity. Patient presents with complaints of right upper quadrant pain, nausea, vomiting. It may be accompanied by cholelithiasis or cholecystitis or both. It is usually diagnosed at an advanced stage when there are only palliative options left. Survival rate is very poor. Conclusion: Leiomyosarcoma of gall bladder should be kept in mind when evaluating a patient with gall bladder mass.