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ARCHAEOSOMES: REVOLUTIONARY TECHNIQUE FOR BOTH CELL-BASED AND DRUG-BASED DELIVERY APPLICATIONS

Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.6, No. 7)

Publication Date:

Authors : ;

Page : 102-127

Keywords : Archaeobacteria; Archaeosomes; Cell Delivery; Drug Delivery; Gene Delivery; Formulations;

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Abstract

Archaeosomes, or liposomes formed with one or more ether lipids specific to the Archaeobacteria domain, are a new kind of liposome discovered in Archaea. Archaeol (diether) and/or caldarchaeol (tetraether) are the basic structures of Achaean-type lipids. Archaeosomes may be made using conventional methods (hydrated film sonicated, extrusion, and detergent dialysis) at any temperature in the physiological range or below, allowing thermally stable chemicals to be encapsulated. Its stability is influenced by a variety of physiological and environmental variables. For cancer vaccines, Chagas disease, proteins and peptides, gene delivery, antigen delivery, and delivery of natural antioxidant chemicals, archaeosomes are extensively utilized as drug delivery systems. The main goal of this review paper was to look at the uses of this novel carrier system in the pharmaceutical sector.

Last modified: 2021-08-03 19:08:49