Analysis of Profile of Blood Transfusion in Patients of Beta Thalassemia: An Experience from Tertiary Care Centre of Jammu Region

Thalassemia is an autosomal recessive blood disorder in which there is reduced rate of synthesis of one of the globin chains that make up the hemoglobin. Ineffective bone marrow erythropoiesis and excessive red blood cell hemolysis together account for the anemia. This study is conducted at a tertiary care hospital and found that 255 (92.39%) patients were diagnosed as Beta thalassemia major, 19 (6.88%) patients were diagnosed as beta thalassemia intermedia and 2 (0.72%) patients suffered from beta thalassemia minor. Out of registered beta thalassemia cases, 243 patients received regular blood transfusion therapy in the form of packed red cells. District-wise distribution of thalassemic patients was observed and found that majority of patients belonged to Jammu and Rajouri districts. Family history of thalassemia was found in 79 (28.62%) of patients.Thalassemia patients comprise the group receiving regular transfusion. Good infrastructure and quality care to these patients is of prime importance. Policies need to be reviewed to provide maximum benefit to these patients.