NOVEL TOPICAL, REGIONAL & TRANSDERMAL DOSAGE FORMS USING NANOTECHNOLOGY: A REVIEW

Purpose: To summarize main findings of topical or transdermal preparation delivered in the skin or eye region using novel nano-technology. Method: Narrative review of all relevant papers from peer reviewed and high impact journals. Results: The delivery system of pharmaceutical preparations for skin and eyes are now elevated to novel aerosolized gels, foams, sprays and other forms that are delivered using nano-pharmaceutical dynamics such as Ag nanoparticles,impregnated urethanes, liposomes, nanoemulsions,polymers and nanopolymers. And these trends provide elevation from benefits and limitations of conventional systems such as enhanced spread and permeation, better bioavailability, prolonged efficacy, reduced toxicity and superior stability. Conclusion: An improved delivery system was made possible by novel discoveries using nano-technology. More and more studies in pharmaceutics are centered on using this technological dynamics to formulate and reformulate drugs that are delivered topically or transdermally.