Prediction of Bowel Gangrene in Intestinal Obstruction using Serum C - Reactive Protein and D - Lactate as Biomarkers

Background: Intestinal obstruction is the one of the most commonly encountered disease in surgical emergency. Strangulation and resulting gangrene is an important complication in terms of both morbidity and mortality of the patients. Early diagnosis and timely surgical interventions improves patient outcomes. Methods: Patients with diagnosis of intestinal obstruction admitted in different surgical units of RIMS, Ranchi during July 2021 - August 2021 were included in this study. A prospective, observational study was conducted with 37 patients. Serum C - Reactive protein (CRP) and D - Lactate were measured pre - operatively and their values were correlated with per - operative findings of bowel ischemia. Result: Serum CRP and serum D - Lactate were found as useful biomarkers in prediction of bowel gangrene in intestinal obstruction.