Intraoperative Cocktail Injection for Pain Management after Total Knee Replacement

Background: Postoperative pain control following total knee replacement is still a big task for early postoperative rehabilitation. Our study was performed to evaluate the outcome of periatricular cocktail injection in patients undergoing TKR with respect to pain and knee motion recovery postoperatively. Method: 80 patients who underwent simultaneous bilateral TKR were included in this study and received intraoperative periarticular cocktail injection in right knee (intervention) while left knee serves as control. Postoperative pain was recorded using VAS for knee. Result: Right knee had significantly less pain as compared to left knee and has shorter period for postoperative 90 degree of knee flexion. Conclusion: Periarticular cocktail injection significantly reduces pain and early knee motion is possible.