Histopathological Evaluation of Renal Tumours - A Two - Year Experience in a Tertiary Care Hospital

Objectives: Study the histopathological spectrum of renal tumours in resected nephrectomy specimens at a tertiary care hospital and to analyse the age as well as sex distribution. Materials and methods: total 54 resected nephrectomy specimens were analysed received in the department of pathology, B J Medical College, Ahmedabad over a two - year period i. e., from May 2019 to August 2021. The clinical details (including age, sex, clinical diagnosis along with radiological details) and gross morphology along with microscopic details were recorded. After gross examination, the tissue was subjected to routine paraffin embedding. A minimum of four sections were taken from the tumour. Sections were cut at 3 - 4 microns on microtome and stained with Haematoxylin and eosin stain (H and E) IHC was not done. The results were tabulated. Results: Out of the total 54 renal specimens, 61.11 % of cases were non - neoplastic and 38.88 % were neoplastic. Out of the neoplastic lesions, 4.76 % were benign and 95.23% were malignant. Most of the patients were in 3rd - 5th decade of life with male to female ratio of 1.62: 1. Histopathologically, RCC - clear cell type was the most common subtype in adults and Wilms tumour in children. Conclusion: RCC is the commonest malignant tumour and clear cell RCC is the most common subtype in adults. Wilms tumour was the most common childhood tumour.