Study of HELLP Syndrome and Maternal and Fetal Outcomes

Aim: HELLP Syndrome is a serious obstetric complication in pregnancy characterized by hemolysis, elevated liver enzymes and low platelet count. Incidence is 0.5-0.9% of all pregnancies and in 10-20% of cases with severe pre ecalmpsia and eclampsia. The aim of this study was to find out the incidence, clinical presentations, severity, complications and maternal and fetal outcome in patients of HELLP Syndrome. Methods: This is a retrospective study done at Civil hospital, asarawa, Ahmedabad. Clinical records of all patients with Pre eclampsia and eclampsia were studied retrospectively. Demographic data, clinical presentation, obstetric complication, mode of delivery and fetal outcome was studied. Results: During the study period there were 5197 deliveries.531 patients had pre eclamspia cases and 131 patients had eclampsia.26 patients developed HELLP Syndrome out of 663 patients. Majority of cases belonged to 21-25 yr of age and having gestational age between 32-37.6wks.53% patients had platelet count below 50, 000.26% of patients required ICU admission.76% patients were preterm. In Present study maternal mortality was 4 % and perinatal mortality was 8%. Conclusion: HELLP Syndrome is a severe variant and catastrophic complication of pre eclampsia and eclampsia. Early diagnosis and early referral to tertiary care unit for final management of HELLP Syndrome results in successful outcome.