A Rare Case of Congenital Varicella in 14 Days-Old Girl Baby

Varicella is a rare disease in infant. Maternal varicella between day 5 antepartum to day 2 postpartum may develop congenital varicella with fatal illness. We reported a 14-days-old girl baby presented with chief complaint widespread pleomorphic rash and fever. Patients complained rash on whole body since 3 days before admitted to hospital. The rash initially appeared on chest then spread to face, both of her hands and feet. Redness spots filled with fluid, ruptured, then dry and form crust. There was history of fever since 4 days before admitted to hospital, with the highest temperature 390C. The patient had laziness to drink. Her mother had fever 2 hours after delivery and varicella rashes 6 hours after delivery. During physical examination, the patient?s body temperature was 38.5?C. Laboratories examination revealed reactive anti-varicella zoster IgM. The mother?s antibody revealed reactive anti-varicella zoster IgG. The patient was administered intravenous acyclovir for 7 days. We don?t have varicella-zoster immune globulin (VariZIG) in our hospital. The lesions recovered on day 9 of treatment and she was discharged. Varicella in the neonates is associated with high morbidity and mortality, but treatment with acyclovir combined with supportive therapy has resulted good outcome.