Lychee Honey Accelerates Antibacterial Efficacy of Penicillin and Amoxiclav Against Gram-Positive Bacteria in Libya | Biomedgrid

Background: The world has left very few of its last line agents to fight against the common infectious diseases due to the rapidly growing phenomenon of bacterial resistance. The present study was thus aimed to rejuvenate the penicillin and amoxicillin-clavulanic acid among the resistant antibiotics supplemented by Lychee Honey as a natural agent. Methods: The study was performed against four-gram positive bacteria where the standard antibiotics and Lychee honey were applied to assess their individual efficacy. Afterwards, the standards were conjugated with lychee honey to evaluate the boosted potential of the combinations. Zone of inhibition, percentage inhibition, minimum inhibitory concentration and minimum bactericidal concentration were observed in this regard. Results: Data suggested that against all four bacteria, lychee honey alone can inhibit the bacterial growth to very little extent whereas the standards showed very mild to medium inhibitory potential. However, the combination of lychee honey with penicillin and amoxiclav separately demonstrated a synergistic action in all tested methods. Conclusion: All findings suggested that lychee honey not only possess inhibitory effect but also facilitates other agents' action, thereby, generating a scope for research for identifying new potential antibacterial agents.