Going Forward with Lymphocytes Immunotherapies for Treatment of Unexplained Recurrent Spontaneous Abortion | Biomedgrid

Recurrent spontaneous abortion (RSA), defined as the occurrence of two or more consecutive miscarriages at less than 22-weeks of gestation [1] , is one of the major pregnancy disorders and affects up to 5% of couples of reproductive ages. Although genetic factors, hormonal diseases, anatomical anomalies and antiphospholipid syndrome have been linked with RSA [2, 3], 50% of cases still remain unexplained and generate growing interest to unveil potential involved mechanisms, particularly for those that imply immunological pathways.