Can Partial Oxygen Pressure Of Urine Be An Indicator For Tissue Perfusion? Review’

The main purpose of advanced monitorisation is to detect hypoperfusion before any irreversible damage. However, none of the advanced monitorisation procedures focusing only on the hemodynamics and blood gas parameters are sufficient to estimate tissue perfusion adequately. As low urine partial oxygen pressure (PuO2 ) is an indicator for medullary hypoperfusion, PuO2 measurement is one of the promising markers for early detection of hypoperfusion. Based on this hypothesis, we had designed a study to evaluate the use of PuO2 together with routine systemic tissue perfusion parameters in patients undergoing open-heart surgery with extracorporeal circulation