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Neurotropic action of soy lecithin in the process of cognitive function formation in white rats

Journal: Medicni perspektivi (Vol.20, No. 1)

Publication Date:

Authors : ; ; ; ; ;

Page : 4-9

Keywords : soy lecithin; polyunsaturated fatty acids (PUFAs); cognitive function;

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In experiments conducted on white rats neurotropic action of soy lecithin, known as a source of unsaturated fatty acids on the background of the neurotoxic impact of CCl4 was studied. Useage of CCl4 by courses showed a significant inhibitory effect that affected the spontaneous behavior of rats “in the open field” by significant inhibition of mobility (44 - 77%), research activity (81%) and increased emotionality (140%). Such usage of soy lecithin having anti-oxidant activity and membrane-stabilizing effect led to optimization of spontaneous behavior of rats. The infringement of cognitive function is, possibly, due to the prooxydative effect of CCl4 and decrease in the unsaturated fatty acid fraction in the structure of the brain lipids. Level of research, mink instinct, emotionality, vertical mobility were restored, and horizontal mobility even increased by 59%. Thus, soy lecithin may be recommended as a drug with correcting cognitive brain function.

Last modified: 2015-04-01 20:23:01