Evaluation of Laparoscopic Single Anastmosis Sleeve Ileal Bypass (SASI) as a Treatment Modality for Morbidly Obese Patients with Type 2 Diabetes Mellitus

The single anastomosis sleeve ileal (SASI) bypass is a Novel Metabolic/Bariatric Surgery operation based on mini gastric bypass operation and Santoro's operation in which a sleeve gastrectomy is followed by a side to side gastro-ileal anastomosis. Amidst the current worldwide epidemic of type 2 diabetes mellitus (T2DM), the global diabetes health burden is projected to reach 522 million in 2030, with much of this increase occurring in developing countries. Aim of the work: to evaluate the role of single anastomosis sleeve ileal bypass (SASI) as a bariatric and metabolic procedure in control of type 2 diabetes in obese patients over one year post-operative. Patients and methods: This prospective cohort study included 40 obese adult patients with type 2 DM. Some of them have other associated comorbidities. They were recruited at department of surgery, Misr University for science and Technology and Al-Azhar University. The follow up was obtained during the first year post-operative. Results: In this study, complete remission of diabetes was achieved in 80% of the patients by the end of the study. This was beside marked weight reduction and improvement of lipid profile without causing micronutrients deficiencies during the study period. Conclusion: SASI bypass can be one of the most efficient metabolic procedures and could be associated with less risks. The procedure should be considered under investigations until enough long term data are available. Thus it is worth to be explored in research aiming for more data.