DIAGNOSTIC ISSUES OF PRIMARY AND SECONDARY FORMS OF MEMBRANOUS NEPHROPATHY

Background. Diagnosis of primary and secondary forms of membranous nephropathy (MN) is based on identifying the clinical features of the course of the disease and morphological changes in the kidney tissue. Objective: to give a comparative description of the main manifestations in primary and secondary forms of MN. Material and methods. Clinical data and results of kidney biopsy of 45 cases of MN were studied, a case from clinical practice was demonstrated. Results. Patients with secondary forms were older (U=91.5; p=0.001), leukocytes in the capillary loops of the glomeruli were more often observed in the kidney tissue (F=0.06; p=0.035), the percentage of global glomerulosclerosis (U=149.0; p=0.037) and interstitial fibrosis (U=144.0; p=0.047) was higher. Conclusion. Diagnosis of primary and secondary forms of MN is important to optimize patient care.