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Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.7, No. 5)

Publication Date:

Authors : ; ; ;

Page : 37-47


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Fast dissolving tablets (FDTs) emerged as one of the popular and widely accepted dosage forms. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia) resulting many incidences of non-compliance and making the therapy ineffective. Specifically for paediatric patients because of incomplete development of the muscular and nervous system and case of geriatric patients suffering from Parkinson's disorder. Oral dosage form and oral route are the most preferred administration route for various drugs with limitations like first-pass metabolism, bedridden, psychiatric patients and uncooperative patients. There is no need of excess water to dissolve and disintegrate FDT tablets. Fast dissolving tablets are designed to dissolve in within 60 seconds in saliva remarkably faster. FDTs formulations contain super disintegrants to enhance the disintegration rate of tablet in the buccal cavity. FDTs have disintegrated quickly, absorb faster so, in vitro drug release time improve and this property of drugs (dosage form) enhanced bioavailability. FDTs have advantages such as easy portability and manufacturing, accurate dosing, good chemical and physical stability and an ideal alternative for geriatric and paediatric patients. FDT formulations have advantage over both conventional tablets and liquid dosage form.

Last modified: 2022-05-27 00:41:03